Instituut voor Neuropathische Pijn

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Welcome to our Institute and Website!

neuron.jpgWelcome to our Institute for neuropathy and neuropathic pain, and our Website. We gathered here for you many articles in the field of neuropathy and neuropathic pain. In our centre we are specialised in treating patients suffering from neuropathic pain and neuropathy following an Integrated Medicine concept. Part of our activities are within the field of consultation. We assist pharmaceutical companies in R&D strategies related to finding new drugs to treat neuropathic pain and neuropathy. 

 In our institute we have a 100% focus on treating patients suffering from neuropathy and neuropathic pain.  

Patients suffering from neuropatic pain are undertreated 

Patients with neuropathy and neuropathic pain are often told: "You just have to learn to live." And patients are also not always well treated. Many of themdo not get enough dose of adequate painkillers, or they are treated with drugs with low or no efficacy against neuropathic pain. [1] [2] [3] [4] And that’s pretty shocking.

For more than 90% of patients with neuropathic pain in the Netherlands is not properly treated! [5] And the quality of life is often very low, even when patients use painkillers! [r = 19254044] [6] [7] We want to make a change!

Nearly 900 articles and thousands of pages

In our website you can review many articles and pages on neuropathy and neuropathic pain. We wrote these articles both for health care professionals as well as for patients.  

You are most welcome to browse and use what you can, if you want, you can copy and paste parts or of articles, provided you include a link to our website.

Jan M. Keppel Hesselink, MD, PhD, Director Research and Development, 


David J. Kopsky, MD, Director Clinical Research,

Institute for Neuropathy and neuropathic pain, Soest, the Netherlands 

*protected email* 

 "Pain is such an uncomfortable feeling that even a tiny amount of it is enough to

ruin every enjoyment."Will Rogers




[1] Oster G, Berger A, Dukes E, Edelsberg J, McCarberg B. | Use of potentially inappropriate pain-related medications in older adults with painful neuropathic disorders. | Am J Geriatr Pharmacother. | 2004 Sep;2(3):163-70.

[2] Gore M, Dukes E, Rowbotham DJ, Tai KS, Leslie D. | Clinical characteristics and pain management among patients with painful peripheral neuropathic disorders in general practice settings. | Eur J Pain. | 2007 Aug;11(6):652-64. Epub 2006 Nov 27.

[3] Lachaine J, Gordon A, Choinière M, Collet JP, Dion D, Tarride JE. | Painful neuropathic disorders: an analysis of the Régie de l'Assurance Maladie du Québec database. | Pain Res Manag. | 2007 Spring;12(1):31-7.

[4] Berger A, Toelle T, Sadosky A, Dukes E, Edelsberg J, Oster G. | Clinical and economic characteristics of patients with painful neuropathic disorders in Germany. | Pain Pract. | 2009 Jan-Feb;9(1):8-17. Epub 2008 Oct 8.

[5] Dieleman JP, Kerklaan J, Huygen FJ, Bouma PA, Sturkenboom MC. | Incidence rates and treatment of neuropathic pain conditions in the general population. | Pain. | 2008 Jul 31;137(3):681-8. Epub 2008 Apr 24.

[6] Hoffman DL, Sadosky A, Alvir J. | Cross-national burden of painful diabetic peripheral neuropathy in Asia, Latin America, and the Middle East. | Pain Pract. | 2009 Jan-Feb;9(1):35-42. Epub 2008 Oct 27.

[7] Liedberg GM, Vrethem M. | Polyneuropathy, with and without neurogenic pain, and its impact on daily life activities--a descriptive study. | Disabil Rehabil. | 2009;31(17):1402-8.

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