Ferulic acid against painful neuropathy
Ferulic acid can kill pain and is an anti-oxidant and anti-aging compound.
Ferulic acid (FA) is a organic compound found in the seeds and leaves of most plants, especially in the brans of grasses such as wheat, rice, and oats. Its chemical structure strongly resembles that of curcumin, and it is mostly extracted from wheat bran.
In an animal model pregabalin (10 mg/kg, p.o.) and ferulic acid (10, 20, 30 mg/kg, p.o.), both significantly and dose dependently, decreased various markers for neuropathic pain: thermal hyperalgesia, mechanical hyperalgesia, and tactile allodynia) as well as a series of biochemical markers (total protein, nitric oxide, lipid peroxidase, and interleukins). 
The compound is produced by plants in high concentrations, when the plants are stressed, so it is a natural protective compound. 
In animal models for memory problems ferulic acid protects the brain.  It also has protective properties in diabetes models. 
July 2016, prof. dr. JMK Hesselink
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