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PERIPHERAL INFLAMMATION IN FIBROMYALGIA

Drs N. Groven and his colleagues from Norway presented a poster at the EFIC in 2017 in Copenhagen, were they explored the peripheral inflammatory character of fibromyalgia. We often recommend palmitoylethanolamide for the treatment of fibromyalgia. This is a supplement based on an endogenous molecule inhibiting inflammation (PeaPlex, Glialia).

Fibromyalgia (FM) patients often experience symptoms similar to those seen in inflammation. Low-grade inflammation can be measured amongst others buy the parameter μ-CRP in blood.

They explored the relationship between low grade inflammation (μ-CRP) and depression in a population suffering from fibromyalgia.

There found significant differences in μ-CRP between the two groups (p = .003) with FM showing higher μ-CRP compared to controls.
Depression scores in FM were also significantly higher than the control group (p = .000). There were no significant correlations between μ-CRP and HADS depression.

Their conclusions are:

FM may be associated with low grade peripheral inflammation.

Slightly elevated levels of μ-CRP in FM are also reported in other studies.

Source: EPD01-CLINICAL/PAIN TREATMENT
Abstract: 16
PERIPHERAL INFLAMMATION IN FIBROMYALGIA SYNDROME
N. Groven1, E. Fors2, V. Iversen1, L. White3, S. Reitan1
1NTNU, Department of Mental Health, Trondheim, Norway
2NTNU, Department of Public Health and Nursing, Trondheim, Norway
3NTNU, Department of Neuromedicine and Movement Science, Trondheim, Norway