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Sodium channel blockers for neuropathic pain

At the European  Pain Federation (EFIC) at Copenhagen, September 2017 there was a plenary section on the management of refractory neuropathic pain, chaired by Dr Andrea Triuni from Italy.


Art this section professor Nadine Attal  presented an overview. She mentioned the sodium channel blockers as a new class of compounds with promising effects in specific populations of neuropathic pain patients.

This indeed is also our experience, as we have meanwhile treated in the Netherlands 200 patients suffering from therapy refractory neuropathic pain by phenytoin cream. Phenytoin is a sodium channel blocker. These results were shared during the discussion and especially interesting was the fact that botulinum injection worked better in patients with intact small fibre density.