Hersenen verschrompelen bij chronische pijn
De hersenen verschrompelen op bepaalde plekken bij chronische pijn. Vooral bij ernstige pijn als CRPS is dat opvallend. Die verandering heet neuroplasticiteit. Tot voor kort dachten we dat pijn alleen tussen de oren zit. Dat zit het ook, maar anders dan we dachten.
We citeren een passage over het verschrompelen van de hersenen bij chronische pijn:
- Altered brain morphology was first shown for CBP patients [9], [10] and is now reported in many pain conditions, including fibromyalgia [11], [12], [13], [14], complex regional pain syndrome (CRPS) [15], osteoarthritis (OA) [16], [17], irritable bowl syndrome [18], [19], [20], headaches[11], [21], [22], [23], chronic vulvar pain [24], in females suffering from menstrual pains [25], as well as in animal models of chronic pain [26], [27]. Across the human studies the most consistent observation is regional decreases in grey matter in the pain patients (although increases and no change are also reported) and, even though many studies emphasize involvement of brain regions associated with pain processes, the data also suggests that unique brain regions are impacted in different types of chronic pain. Most importantly, it remains unclear whether morphological reorganization exclusively impacts pain processing circuitry and whether the sites of local reorganization mirror specific patterns of brain functional states seen for distinct types of chronic pain (for differing views see [2], [17], [28], [29]).
Hersenen kunnen weer normaal worden
En wat minstens zo belangrijk is, is dat de hersenafwijkingen bij goede behandeling weer afnemen. Wel is het zo, dat hoe langer je pijn hebt gehad, hoe langer het duurt voordat je hersenen weer normaal worden.[1]
- Recent studies demonstrate that many of the gray matter changes observed in pain patients subside with cessation of pain [16], [17], [30]. In addition, it has been shown that the observed morphological differences in chronic pain conditions often correlate to the number of years of pain individuals have been suffering with the condition as well as its intensity [9], [12], [15], [28]. These results suggest that the brain morphological changes may be reversible in nature and are a consequence of pain perception.
Daarom is tijdige en goede behandeling van chronische pijn een must!
December 2011,
Bekijk hier video’s van onze patiënten over neuropathie.
Ook interessant…
Pijnstillende crèmes • Clonidine crème • Ketamine crème • SOLK of MOK? • Cannabis bij DVN • Vragen over Cannabis • CIAP aanpakken
[1] Baliki MN, Schnitzer TJ, Bauer WR, Apkarian AV. | Brain morphological signatures for chronic pain. | PLoS One. | 2011;6(10):e26010. Epub 2011 Oct 13.